Separation columns). These substances are real magnetic fluids, and the magnetic isolation is only possible with a High Gradient Magnetic Separator (e. g. Terminal functional groups such as ion-exchange groups or reactive groups for covalent immobilization can be used for binding to biomolecules. This is expensive and time consuming; Ferrofluids can further be used for MRI-diagnostics and magnetic drug targeting applications. fluidMAG -nanoparticles with hydrodynamic diameters of 100-200 nm have a multi-domain core and in-batch separable by a external magnetic field (magnetic separator). Therefore, a fast and easy magnetic isolation of nanoparticles is possible. Ferrofluids with particle sizes of 50 nm have a single domain core and therefore not separable by an external magnetic field.
fluidMAG -nanoparticles are ferrofluids consisting of an aqueous dispersion of magnetic iron oxides with diameters of 50 nm, 100 nm and 200 nm.
Therefore we recommend using magnetic nanoparticles with a minimum size of 100 nm. The particles are covered with hydrophilic polymers which protect them against aggregation by foreign ions. Magnetic nanoparticles thesis.